Estriol 0.01% Cream - 80g

Vaginal Dryness

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  • Estriol 0.01% Cream - 80g

Estriol 0.01% Cream - 80g

Vaginal Dryness
  • Medication features

    Estradiol cream is a hormone replacement therapy for treating the symptoms of menopause. It's applied inside the vagina and contains just oestrogen.

    • Treats a variety of symptoms
    • Easy to apply
    • For female use only


NOTE: After selecting this product, you will need to complete a short assessment, so we can make sure this medication is suitable for you. Pricing is provided as a reference only. The final decision on issuing this medication remains with our Prescriber / Pharmacist.

Estriol cream is a hormone based treatment for women going through the menopause. The shortage of estrogens during the menopause may cause the vaginal wall and its lining to become dry and thin. This can lead to pain during intercourse and an increase in itching/irritation which can cause infections. By replacing estrogen via the vaginal cream Estriol the patient can see a reduction in symptoms and maintain balance during the menopause.


Why would I choose a vaginal cream such as Estriol over oral tablets? By using Estriol you will be able to lower plasma levels of estrogen and have greater effectiveness at controling localised symtoms compared to a tablet

How long does Estriol take to work? It can take several days or even weeks for Estriol to be effective. It is best to use the cream regularly for results to be most effective. 

  • What is Estriol Cream?

    Estriol cream treats the vaginal symptoms of menopause – it is a common choice of topical treatment used to treat symptoms such as vaginal inflammation, dryness and painful sex. Menopause causes your sex hormones to decline gradually. Symptoms occur due to the decline in the main female sex hormone, oestrogen. Estriol is a type of hormone replacement therapy (HRT) which helps women to manage their symptoms better by replacing the declining hormones.

    How does it work? – topical HRT like Estriol improves symptoms affecting the vagina, which are caused by a lack of oestrogen. The active ingredient in the cream is estriol, which is a type of oestrogen. It is one of three main oestrogens produced by your body. This adds extra oestrogen to your vagina, which helps to relieve symptoms.

    How do you use it? – the cream comes in a pack with a clear plastic applicator, which is used to apply the cream into your vagina. The applicator has a ring marked on the body which indicates where you need to fill the cream up to for the correct dose. See the section of this page called 'how to use estriol for more information.

  • How do I buy Estriol cream online?

    You can order your estriol cream from us online – our quick and easy service provides a convenient way of getting your medicine without having to order a repeat prescription from your GP or collecting your medicine from a local pharmacy.

  • How else can I buy estriol cream?

    It is only available on a prescription. You would need to get an assessment and a prescription from a doctor and then get your prescription filled in pharmacy.

Side Effects

Patients may experience irritation of the skin, itchiness, vaginal discharge, bleeding, spotting, swollen tender breasts and headaches. Some patients may also experience nausea and vomitting.


Info Leaflet

Before taking any medicines, regardless of whether they are over the counter or prescription-only, it is essential always to read the patient information leaflet.

Patient Information Leaflet