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Kliovance

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Kliovance

Kliovance tablets are a hormone replacement therapy (HRT) that may reduce menopausal symptoms such as hot flushes, poor sleep, vaginal dryness, night sweats, and mood swings. Kliovance is a low-dose continuous combined HRT, taken as one tablet every day without a break. This HRT is suitable for postmenopausal women and contains oestradiol and norethisterone.

  • For women going through menopause
  • Relieve menopause symptoms like hot flushes and night sweats
  • Simple one-a-day tablet dosage

Kliovance is an oral continuous combined HRT for women who still have a womb (uterus) and whose last period was more than 1 year ago. Each tablet contains estradiol 1mg and norethisterone acetate 0.5mg, and you take one tablet every day without a break.

As with all medications that relieve menopause symptoms, you may experience side effects with Kliovance tablets. Most side effects are mild and will go away over time. However, there are some side effects that can cause health problems or disrupt your daily life. If you are worried about certain side effects, you should contact your doctor to discuss these issues straight away. If you are concerned about side effects before you decide which treatment to choose, you can contact a member of our team who will be happy to help you.

Some side effects of Kliovance tablets may include:

  • Vaginal bleeding
  • Genital thrush or vaginal inflammation
  • Abdominal pain
  • Headaches
  • Depression
  • Nausea
  • Weight gain
  • Swelling caused by fluid retention (oedema)
  • Breast pain or tenderness
  • Back pain
  • Leg cramps

There are few serious side effects associated with taking oral HRT. Seek medical attention as soon as possible if you experience swelling in the lower leg that is inflamed and hot to touch.

When I buy Kliovance online, what are the risks involved in using this hormone replacement therapy (HRT)?

Hormone replacement therapy (HRT) comes with some risks that need to be considered before starting treatment, which can be discussed in your consultation. With all medications such as Kliovance tablets, there are ways to minimise risks and having regular check-ups will ensure that any risks from using HRT are monitored and minimised.

It is important to note that studies suggest that combined HRT tablets can cause a slightly increased chance of developing breast cancer, blood clots or strokes. Although these risks are small, it is advised to take these into consideration before treatment and to discuss concerns about these risks with your doctors. During your treatment, your doctor should monitor these potential health risks regularly. You should also ensure that you attend regular breast cancer screenings in order to monitor risks throughout your treatment.

Leaflets

Before taking any medicines such as Kliovance tablets, regardless of whether they are over-the-counter or prescription-only, it is essential always to read the patient information leaflet.

Patient Information Leaflet

Umar Razzaq, MPharm | University of Strathclyde, Clinical Pharmacist.
Content Written by:Umar RazzaqMPharm | GPhC Reg: 2064448 | University Of Strathclyde
Date Written:12/06/2026
Role:Clinical Pharmacist
Nish Fayyaz, MPharm | University of Strathclyde, Pharmacist.
Medically Reviewed By:Nish FayyazMPharm | GPhC Reg: 2225257 | University Of Strathclyde
Date Checked:12/06/2026
Role:Pharmacist
Fully inspected and regulated service
UK registered pharmacy
Approved UK-licensed treatments
Discreet next day delivery