Mounjaro Doses: The Complete Mounjaro Dosage Chart and Titration Guide
Mounjaro is a once-weekly weight loss injection that comes in six different dose strengths. Each Mounjaro dose is administered with the KwikPen, and you begin with the lowest dose, gradually increasing it weekly until you reach your optimal maintenance dose (titration).
Mounjaro is a once-weekly weight loss injection that comes in six different dose strengths. Each Mounjaro dose is administered with the KwikPen, and you begin with the lowest dose, gradually increasing it weekly until you reach your optimal maintenance dose (titration).
In this guide, we'll explain each dose strength, how titration works, maintenance doses, and how to stick to your dosing schedule.
Mounjaro Dose Strengths
When you first begin taking Mounjaro, you'll start on the lowest strength, then gradually increase it until you reach the maintenance dose.
| Dose Strength | When Used | Pen Contains | Notes |
|---|---|---|---|
| 2.5 mg | Weeks 1–4 (starting dose) | 4 weekly doses | The starting dose for all new patients. This dose is also used after a break of 2+ weeks |
| 5 mg | Weeks 5–8 (minimum) | 4 weekly doses | First maintenance dose option for patients that respond well to the treatment and achieve good results. |
| 7.5 mg | Weeks 9–12 (minimum) | 4 weekly doses | Most standard maintenance dose according to some UK prescribers. |
| 10 mg | Weeks 13–16 (minimum) | 4 weekly doses | Increased to 10mg up if weight loss or blood sugar control are insufficient. |
| 12.5 mg | Weeks 17–20 (minimum) | 4 weekly doses | Intermediate step before moving onto the maximum dose. |
| 15 mg | Week 21+ (maximum dose) | 4 weekly doses | The maximum licensed dose available. Not everyone needs to reach this. |
Note: While the standard titration process increases doses in four-week increments, your prescriber might recommend increasing the doses more slowly. It's essential to follow the instructions and never increase your dose without express advice from a healthcare professional.
The Mounjaro Titration Schedule: Step by Step
Mounjaro is an effective medication, but its strength means that titration is a core part of your weight loss treatment. Titration is a process in which your prescriber will start you on the lowest dose and gradually increase it as your body gets used to the treatment.
It's designed to minimise side effects and monitor how your body responds to the treatment plan.
The Standard Titration Path
| Month | Dosage | Notes |
|---|---|---|
| 1 | 2.5 mg | Everyone starts on 2.5 mg, including people using Mounjaro for weight loss and diabetes management. The only exception is when you're switching from another GLP-1 medication, as your prescriber may recommend a higher starting dose. |
| 2 | 5 mg | If your body tolerates the 2.5 mg dose well, you'll move onto the 5mg injections. Some people remain on this strength if they experience sustained weight loss. |
| 3 | 7.5 mg | Your prescriber may increase your dose to 7.5 mg if you need better blood sugar control or aren't seeing consistent weight loss. |
| 4 | 10 mg | Your prescriber may recommend increasing the dose to 10 mg when you tolerate the injections well and your weight loss has plateaued. |
| 5 | 12.5 mg | The 12.5 mg dose can help if you notice your appetite begins to increase or you experience cravings. Again, this depends on how your body responds to the treatment. |
| 6 | 15 mg | As the maximum maintenance dose, 15 mg isn't given to everyone. If your prescriber feels that you might benefit from the maximum dose they'll discuss it with you. |
The four-week increments are a guideline only. Your healthcare provider will never increase your dose earlier than this, but they may recommend that you stay at a lower dose for longer.
Some people respond well to the lower-maintenance dose of 5mg, while others may need to increase their dose for optimal appetite control and weight management. A slower titration schedule doesn't reduce the effectiveness of your medication.
Do You Have to Reach 15 mg?
No, you don't. The 15mg dose is the maximum maintenance dose, but it's not essential. Your prescriber will always try to find the right maintenance dose for your needs, which means the lowest option that provides consistent results.
Eli Lilly lists 5 mg, 10 mg, and 15 mg as official Mounjaro maintenance doses, but your recommended strength depends on how you respond to the treatment.
Some prescribers will recommend the standard maintenance dose of 7.5, while others will personalise your treatment.
Clinical studies show that higher doses result in more weight loss. For example, progressing from 5 to 15 mg can increase weight loss by 6-7% (NIH). But this doesn't mean that 15mg is right for you, as you may not need the maximum strength to reach your goal weight.
It's also important to remember that higher strengths are usually more expensive, which means that private patients need to weigh up the potential costs with weight loss.
If you reach your goal weight with a lower dose, there's no need to increase it.
How to Know When to Increase Your Dose?
Your prescriber will review your progress throughout your treatment, assessing whether you're losing weight steadily. If you initially experienced success but your weight-loss journey has slowed, they may consider increasing your dose.
Individuals with type 2 diabetes may have dose increases when they don't meet their blood sugar targets (HbA1c or fasting glucose) after at least four weeks on a certain strength.
It also depends on your side effects and whether your body is tolerating the dose well. Never increase your dose without express recommendations from the prescriber.
The Mounjaro KwikPen: What You Need to Know About Doses
Each Mounjaro KwikPen has 4 pre-measured doses of 0.6 ml, so each pen lasts for a month. Each strength comes in a different pen, and you should never share them with anyone.
Store unused pens in the fridge at 2–8°C, then keep them at room temperature for up to 30 days once you're using them. It's important to note that needles aren't included, so you'll need to ensure you use compatible pens.
The KwikPen 2026 Update
From April 2026, UK pharmacies have been rolling out an updated KwikPen. It works the same as the traditional pen, but reduces excess liquid after your fourth dose (also known as the "golden dose").
Both pen designs may be circulating during this transition, so don't worry if they look slightly different.
The Golden Dose: What It Is and Why You Shouldn't Use It
The "Golden Dose" occurs when you've completed the four doses in a single pen but there's some residual liquid. People call this the "fifth" or "magic" dose, but it's actually a deliberate overfill that ensures the accurate delivery of each prescribed Mounjaro dose.
Eli Lilly makes it clear that you shouldn't use any medication left in the pen, as the remaining amount varies and isn't an accurate measurement. Trying to use it can also increase the risks of infection and contamination.
The upgraded 2026 KwikPen reduces this leftover liquid, making this less of an issue going forward. If the cost of your treatment is your primary reason for considering this liquid, speak to your prescriber about potentially lowering the dose or switching to an alternative GLP-1 treatment.
What to Do If You Miss a Dose
If you miss a dose of Mounjaro and it's been four days or less, take the dose as soon as you remember, then continue your weekly injection schedule. However, if more than 4 days have passed, skip the missed dose and continue your regular schedule.
Never double up or inject Mounjaro more than once weekly. If you've stopped Mounjaro for two weeks or longer, you'll have to restart at the 2.5 mg dose to reduce side effects and give your body time to adjust.
Please get in touch with your prescriber if you've missed multiple doses and are unsure of what to do.
Switching from Wegovy or Another GLP-1 Injection
If you're switching from another GLP-1 medication like Wegovy (semaglutide), you might not have to restart at your 2.5 dose. The prescriber will assess how your body responded to the other treatment and what strength you're currently using before recommending the Mounjaro starting dose.
For example, if you were using 2.4 mg of Wegovy, your prescriber may let you start at 5 mg or 7.5 mg. Again, this is an individual clinical decision, and it's vital to follow your prescriber's advice.
How many doses are in a Mounjaro pen?
Each Mounjaro pen contains four doses, and you'll switch pens each month. The small amount of residue left in each pen isn't a fifth dose.
What is the starting dose of Mounjaro?
Everyone begins treatment at 2.5 mg of Mounjaro unless you're switching from another GLP-1 medication.
What is the maximum dose of Mounjaro?
The maximum dose of Mounjaro is 15 mg. However, it's not the recommended dose for everyone, and your prescriber may recommend sticking to your current dose if your Mounjaro treatment is working.
How often can you increase your Mounjaro dose?
It depends on your individual circumstances. The minimum interval between dose increases is 4 weeks, but this is only a guideline. Some people may benefit from longer periods between doses, based on how they respond to the treatment and Mounjaro side effects.
What if I miss a Mounjaro injection?
If you miss a dose of Mounjaro and it's within four days of the scheduled day, you can take it as normal. If it's over four days, you should skip the dose and continue with your regular schedule.
What is the Mounjaro golden dose?
The Mounjaro golden dose refers to the excess liquid after your four doses. You shouldn't use this as a fifth dose, as it's a deliberate overfill.
Can you stay on a lower Mounjaro dose long term?
There are different Mounjaro doses available for sustainable weight loss. If your body responds well to a lower maintenance dose and you continue to lose weight, there's no need to increase it.
