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Nexium

Nexium tablets provide effective relief for acid reflux and indigestion. This helps to calm symptoms such as heartburn, chest discomfort and hiccups. The branded version of esomeprazole, Nexium gastro-resistant tablets, works by reducing the amount of gastric acid the stomach produces. You can buy Nexium online from Pharmacy Online.

  • An effective treatment for acid reflux & heartburn
  • Branded version of Esomeprazole

Buy Nexium 20mg Tablets Online

Nexium contains the active ingredient esomeprazole, which is used to treat acid reflux and similar conditions, including gastro-oesophageal reflux disease (GORD) and heartburn.

Nexium (esomeprazole) helps prevent reflux symptoms associated with excess stomach acid by inhibiting the activity of certain cells in the stomach lining that produce acid.

With reduced stomach acid production, less acid reflux back into the gullet (oesophagus). Nexium works best when taken regularly in a daily dose.

You can buy Nexium 20mg tablets here at Pharmacy Online. Simply start a consultation with our online doctor to get your prescription started. Here, you’ll be asked a few simple questions to approve your prescription.

When to Use Nexium 20mg?

Nexium is the branded version of the generic esomeprazole, containing the same strength and form. This medicine is part of a group of drugs known as proton pump inhibitors (PPIs) used to treat:

  • Gastroesophageal reflux disease (GERD)
  • Ulcers infected with Helicobacter Pylori bacteria
  • Stomach ulcers caused by NSAIDs
  • Acid reflux
  • Zollinger-Ellison syndrome, where you produce too much stomach acid.

Age Restrictions For Nexium 20mg

Nexium tablets are licensed for adults and adolescents aged 12 and over. They are not recommended for children under 12; a different form of esomeprazole (granules in sachets) is used for children aged 1 to 11.

How to Use Nexium 20mg Tablets?

When using Nexium, please follow these instructions carefully:

  • Dosage: Take 1 tablet daily. You can take it at any time of the day, with food or on an empty stomach.
  • Taking the Tablet: It's best to swallow the tablet whole with a glass of water. However, if you have problems swallowing, you can dissolve the tablet in water.

It's best to take the tablet at the same time each day for optimal benefits.

When to Avoid Using Nexium?

While Nexium is generally safe, there are some situations where you should avoid using it. These include:

  • Allergies: If you've experienced reactions to PPIs before or are sensitive to any of the ingredients in Nexium, you should avoid using it.
  • HIV Treatment: Do not take Nexium if you take nelfinavir (an HIV medicine). Taking it with atazanavir (another HIV medicine) is not recommended. If you're using Rilpivirine (an HIV treatment), taking Nexium can impact its absorption.

Precautions For Nexium 20mg

You should consult your healthcare professional before using Nexium if you have:

  • Severe Liver Problems: The OTC dose of Nexium is usually suitable for the liver, but individuals with severe liver disease should seek medical advice first. You may also require regular blood tests when using the tablets.
  • Low Magnesium: Long-term Nexium use can decrease your magnesium levels, leading to deficiencies and side effects.
  • Osteoporosis: PPIs can also affect calcium absorption, worsening osteoporosis symptoms.
  • Pregnancy or Breastfeeding: Please speak to a doctor or registered pharmacist before using PPIs if you're pregnant or breastfeeding.

Ingredients Of Nexium 20mg

The main ingredient in Nexium is Esomeprazole Magnesium (22.3mg). It's a PPI that reduces stomach acid.

Inactive Ingredients include:

  • Glyceryl monostearate
  • Hypromellose
  • Hydroxypropyl cellulose
  • Iron oxide
  • Magnesium stearate
  • Polysorbate 80
  • Polyethene glycol,
  • Methacrylic acid copolymer type C
  • Titanium dioxide
  • Talc
  • Sugar spheres (sucrose and maize starch)

Nexium contains sugar spheres which contain sucrose, a type of sugar. If you have been told by your doctor that you have an intolerance to some sugars, talk to your doctor before taking this medicine.

Side Effects Of Nexium 20mg

There is always a risk of side effects with all medications. Some of these can be quite mild and can subside over time.

Others are more serious and should be reported to your GP right away if you experience any side effects. Please contact a member of our team if you are concerned about potential side effects when taking Nexium.

If you experience a severe rash, breathing difficulties, or other symptoms, it can be a sign of a severe allergic reaction.

Common side effects include:

  • Nausea
  • Diarrhoea
  • Abdominal pain
  • Constipation
  • Headache
  • Vomiting
  • Wind (flatulence)
  • Harmless (benign) polyps in the stomach

Uncommon side effects (may affect up to 1 in 100 people) include:

  • Dizziness
  • Dry mouth

There are some rare yet severe side effects associated with Nexium.

For example:

  • Blurred vision
  • Disturbed sleep
  • Sudden wheezing
  • Generally feeling unwell
  • Reduced number of white blood cells, leading to an immune deficiency
  • Joint pain along with a red skin rash, e.g. severe blisters and itchy skin, especially in parts of your body exposed to the sun, such as your arms, cheeks and nose.
What is the difference between prescription and over-the-counter Nexium?

Prescription and over-the-counter Nexium both contain the same active ingredients to tackle acid reflux and work in the same way.

However, over-the-counter medications may contain a lower dosage. You can get a prescription for Nexium 20mg here at Pharmacy Online.

Is Nexium Safe?

Taking Nexium for a long time can increase the risk of some side effects. Taking it for more than a year may slightly increase the risk of fractures of the hip, wrist or spine, and long-term use can lower magnesium levels (possible after 3 months or more) and reduce how well you absorb vitamin B12. Harmless (benign) polyps in the stomach are also a common side effect.

Your doctor can advise you on the recommended dosage and duration to treat your condition. An acid-damaged gullet (oesophagitis) is usually treated with 40mg a day for 4 weeks, with a further 4 weeks if it has not healed, and reflux symptoms with 20mg a day. If 4 weeks of treatment has not settled your symptoms, see your doctor. Some people then continue on 20mg a day, or take it when needed, to keep symptoms away, and people at risk of ulcers from NSAID painkillers may take it for as long as they take the NSAID.

Nexium can hide symptoms of other diseases, so speak with your doctor immediately if you experience:

  • Black stools
  • You lose weight unexpectedly
  • Problems swallowing
How do you take a proton pump inhibitor?

Nexium tablets can be taken at any time of the day, with food or on an empty stomach. Take a missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Do not take a double dose.

How long will I have to keep taking PPIs?

PPIs are generally taken for 2 to 8 weeks, depending on the condition being treated.

Can I drink alcohol?

The Nexium leaflet does not list alcohol as an interaction. If you have any questions about drinking alcohol while taking it, ask your doctor or pharmacist.

What time of day to take Nexium?

Nexium can be taken at any time in the day, as long as it is taken consistently at the same time each day.

You can take Nexium with food or on an empty stomach.

Where can I buy Nexium?

You can buy Nexium 20mg here at our UK pharmacy, Pharmacy Online. Arranging your prescription is easy; simply start an online consultation with our online doctor. Once ordered, we deliver your prescription straight to your door. All medicines can be sent with next-day delivery.

Nexium 20mg Patient Information Leaflet

Before taking any medicines, whether over the counter or prescription-only, it is essential to always read the Patient Information Leaflet. If you have any questions or require advice, our registered pharmacists are here to help. Please contact us today.

Umar Razzaq, MPharm | University of Strathclyde, Clinical Pharmacist.
Content Written by:Umar RazzaqMPharm | GPhC Reg: 2064448 | University Of Strathclyde
Date Written:12/06/2026
Role:Clinical Pharmacist
Nish Fayyaz, MPharm | University of Strathclyde, Pharmacist.
Medically Reviewed By:Nish FayyazMPharm | GPhC Reg: 2225257 | University Of Strathclyde
Date Checked:12/06/2026
Role:Pharmacist
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